Lazarus of Bethany is honored as a saint by those Christian churches which keep the commemoration of saints, although on different days, according to local traditions.

In the Eastern Orthodox Church as well as the Byzantine Catholic Church, the day before Palm Sunday is celebrated as Lazarus Saturday. This day, together with Palm Sunday, hold a unique position in the church year, as days of joy and triumph between the penitence of Great Lent and the mourning of Holy Week.During the preceding week, the hymns in the Lenten Triodion track the sickness and then the death of Lazarus, and Christ's journey from beyond Jordan to Bethany. The scripture readings and hymns for Lazarus Saturday focus on the resurrection of Lazarus as a foreshadowing of the Resurrection of Christ, and a promise of the General Resurrection. The Gospel narrative is interpreted in the hymns as illustrating the two natures of Christ: his humanity in asking, "Where have ye laid him?" (John 11:34), and his divinity by commanding Lazarus to come forth from the dead (John 11:43). Many of the Resurectional hymns of the normal Sunday service, which are omitted on Palm Sunday, are chanted on Lazarus Saturday. During the Divine Liturgy, the Baptismal Hymn, "As many as have been baptized into Christ have put on Christ" (Romans 6:3), is sung in place of the Trisagion. Although the forty days of Great Lent end on the day before Lazarus Saturday, the day is still observed as a fast; however, it is somewhat mitigated. In Russia, it is traditional to eat caviar on Lazarus Saturday.

In the Roman Catholic Church Saint Lazarus' memorial is on June 21. In Cuba a major festival is dedicated to San Lzaro.

He is commemorated in the Calendar of Saints of the Lutheran Church on July 29 together with Mary and Martha.

In Christian funerals the idea of the deceased being raised by the Lord as Lazarus was raised is often expressed in prayer.